Maladies des voies urinaires, Nephrology.
Urinary tract diseases, Néphropathies. Pathologie vasculaire rénale.
Insuffisance rénale, Nephropathies. Renovascular diseases. Renal failure, Insuffisance rénale, Renal failure, Endocrinopathies, Pancréas endocrine.
Cellules apud pathologieEndocrine pancreas. Apud cells diseasesDiabète.
Anomalie tolérance glucose, Diabetes. Impaired glucose tolerance, Etiopathogénie. Résistance tissu cible, Etiopathogenesis.
Phenylalanine is converted to para- and ortho-tyrosine by hydroxyl free radical, or to para-tyrosine by the phenylalanine hydroxylase enzyme. In our cross-sectional study we measured para- ortho-tyrosine, and phenylalanine levels, using high performance liquid chromatography and 8-epi-prostaglandin-F2α with enzyme-linked immunosorbent assay ELISA.
There was no difference in the plasma ortho-tyrosine levels between the groups.
The difference between para-tyrosine levels of the groups is probably due to renal impairment, while there is indirect evidence for an increased tubular secretion or production of ortho-tyrosine in the kidney in diabetic patients with or without CKD.